| T2763 |
Panaxadiol
|
20(R)-Panaxadiol |
Others
,
HIF/HIF Prolyl-Hydroxylase
|
|
Panaxadiol (20(R)-Panaxadiol) is a novel antitumor agent extracted from the Chinese medical herb Panax ginseng. |
| Fr16745 |
4-Hydroxybenzyl cyanide
|
4-Hydroxyphenylacetonitrile |
Endogenous Metabolite
|
|
4-Hydroxybenzyl cyanide (4-Hydroxyphenylacetonitrile) shows strong antioxidative activity. |
| TN1376 |
α-Solanine
|
alpha-Solanine |
MMP
,
Akt
,
PI3K
|
|
Alpha-Solanine alters antioxidative enzyme activities and MDA and PCO concentrations and GST activity in fat body and midgut. |
| T16747 |
Riboflavin Tetrabutyrate
|
|
Reactive Oxygen Species
|
|
|
| TN1160 |
1,2,3,6-Tetragalloylglucose
|
1,2,3,6-Tetra-O-galloyl-β-D-glucose,TeGG |
LDL
,
UGT
|
|
1,2,3,6-Tetragalloylglucose (TeGG) has antioxidative activity, it also shows the most potent anticomplement activity (IC50 = 34 microM). 1,2,3,6-Tetragalloylglucose is also a potent inhibitor of UDP glucuronosyltransfera... |
| T4S1718 |
Punicalin
|
|
HBV
,
HIV Protease
|
|
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM). |
| T5796 |
Plantainoside D
|
Isoplantamajoside |
RAAS
,
PKC
|
|
Plantainoside D (Isoplantamajoside) shows potent antioxidative effects as those of ascorbic acid, it shows angiotensin-converting enzyme (ACE) inhibitory inhibitory activity in vitro with the IC(50) value of 2.17 mM, it ... |
| T2770 |
Gentiopicroside
|
Gentiopicrin |
P450
,
HCV Protease
|
|
Gentiopicroside (Gentiopicrin), a naturally occurring iridoid glycoside, extracted from Gentiana manshurica Kitag, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; has antianti-inflammatorya... |
| T3903 |
Angoroside C
|
|
Prostaglandin Receptor
|
|
Angoroside C is a Potential anti-inflammatory compound. Inhibitor of prostaglandin E2 release in mouse peritoneal macrophages in vitro. Shows potent antioxidative activity in reducing the oxidized OH adducts of dAMP and ... |
| T6102 |
2'-acetylacteoside
|
|
Antioxidant
,
Reductase
|
|
2'-Acetylacteoside has antioxidative activity. It can significantly attenuate glutamate-induced neurotoxicity at concentrations ranging from 0.1 to 10 μM. 2'-Acetylacteoside shows antiproliferative effects on aortic smoo... |
| T3907 |
Tenuigenin
|
Senegenin,Senegin |
NF-κB
,
Caspase
,
Antibacterial
|
|
Tenuigenin (Senegenin) is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity. |
| T3857 |
Magnolin
|
(+)-Magnolin |
ERK
|
|
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects. |
| T2212 |
Geniposide
|
|
Beta Amyloid
,
Influenza Virus
|
|
Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation... |
| TN1644 |
Flavanomarein
|
|
Others
|
|
Flavanomarein demonstrates potent antioxidative property, including free radical scavenging activity, inhibition of lipid peroxidation, as well as lipid-lowering effects in human HepG2 hepatocellular carcinoma cells trea... |
| T4S0094 |
Hydroxygenkwanin
|
Luteolin 7-methylether,7-O-Methylluteolin |
Antioxidant
|
|
1. Hydroxygenkwanin (Luteolin 7-methylether) possesses significant the antioxidative activity . 2. Hydroxygenkwanin has cytotoxicity, may be an effective natural product to treat glioma, and the combination of Apigenin a... |
| TN1873 |
Lirinidine
|
|
Others
|
|
(+)-Lirinidine has antioxidative activity, and it can significantly inhibit the proliferation of melanoma cells; it also shows potent inhibition of melanogenesis. Lirinidine exhibits significant inhibition of collagen, a... |
| T5S2059 |
Glaucine
|
|
Calcium Channel
,
Dopamine Receptor
,
Influenza Virus
,
Adrenergic Receptor
,
PDE
|
|
Glaucine has antitussive, antioxidative potential and antiviral activities, it may be an anti-arthritic agent, it can enhance LPS and zymosan-induced IL-10 production. Glaucine can inhibit the migration and invasion of h... |
| T3S0645 |
N-trans-Feruloyltyramine
|
Feruloyltyramine,N-Feruloyltyramine,Moupinamide |
Others
,
COX
|
|
1. N-trans-Feruloyltyramine (Feruloyltyramine)(NTF) has hepatoprotective effect. 2. NTF has antioxidative activity against Aβ(1-42)-induced neuronal death. 3. NTF is likely to inhibit COX enzymes, thereby suppressing P-s... |
| T6S0525 |
Farrerol
|
|
ERK
,
p38 MAPK
,
Akt
|
|
1. Farrerol has antioxidative activity.2. Farrerol modulates TAP and BNBD5 gene expression in mammary gland, enhances bMEC defense against S. aureus infection and could be useful in protection against bovine mastitis. 3.... |
| TN2387 |
7,8,9,9-Tetradehydroisolariciresinol
|
|
Antioxidant
|
|
7,8,9,9-Tetradehydroisolariciresinol has antioxidative activity |
| TN6488 |
Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside
|
|
|
|
Orcinol 1-O-beta-D-apiofuranosyl-(1->6)-beta-D-glucopyranoside has antioxidative activity. |
| T3S2210 |
Lancerin
|
|
Others
|
|
Lancerin, extracted from the root bark of Cudrania cochinchinensis, exhibits antioxidative activity against lipid peroxidation. |
| TN2680 |
2,2-Dimethyl-8-prenylchromene 6-carboxylic acid
|
|
Others
|
|
2,2-Dimethyl-8-prenylchromene 6-carboxylic acid showed antioxidative activity. |
| TN3668 |
Cis-Miyabenol C
|
|
Others
|
|
cis-Miyabenol C exhibits antioxidative activities and shows strong hyaluronidase inhibitory effects. cis-Miyabenol C also has ecdysteroid antagonist activity. |
| TN4872 |
Pyrroside B
|
|
ROS
|
|
Pyrroside B shows stronger antioxidative activity than that of α-tocopherol. |
| TN1581 |
Dihydroguaiaretic acid
|
|
COX
,
DNA/RNA Synthesis
|
|
Dihydroguaiaretic acid has antioxidative activity, can significantly protect primary cultured neuronal cells against glutamate-induced oxidative stress. |
| TN3030 |
4-Galloylquinic acid
|
|
Others
|
|
4-Galloylquinic acid shows some antioxidative activity. |
| TN2114 |
Pseudoginsenoside Rh2
|
|
ERK
,
Raf
,
p53
|
|
Pseudoginsenoside Rh2 has cytotoxicity, it induces mitochondrial apoptosis in A549 cells and is responsible for excessive activation of the Ras/Raf/ERK/p53 pathway. (20Z) -Pseudoginsenoside Rh2 and (20E)-Pseudoginsenosid... |
| TN5189 |
Tristin
|
|
Others
|
|
Tristin shows stronger antioxidative activity than butylated hydroxyanisole (BHA). |
| TN2129 |
Quercetin-3-o-rutinose
|
|
Others
|
|
Quercetin-3-o-rutinose has antioxidative activity, it exerts strong DPPH radical-scavenging activity. |
| TN4650 |
Nervogenic acid
|
|
Antifection
|
|
Nervogenic acid has antioxidative, pro-coagulant, and antibacterial activities, it exhibits higher activity than that of t-butyl-4- hydroxyanisole (BHA) using the ferric thiocyanate method. |
| TN5329 |
Epitulipinolide diepoxide
|
|
|
|
Epitulipinolide diepoxide has antioxidative and chemopreventive activities in skin melanoma cells, can significantly inhibit the proliferation of melanoma cells, it possesses cytotoxic activity against KB cells. |
| TN5240 |
Vitedoin A
|
|
Others
|
|
Vitedoin A shows stronger antioxidative activity than alpha-tocopherol using the ferric thiocyanate method, it also shows higher radical-scavenging effect on the stable free radical, 1,1-diphenyl-2-picrylhydrazyl, than L... |
| TN1536 |
Curculigoside B
|
|
Others
|
|
Curculigoside B shows antioxidative and antiosteoporotic activities, it can decrease area of bone resorption pit, osteoclastic formation and TRAP activity. |
| T83588 |
(±)-Coclaurine
|
|
|
|
(±)-Coclaurine, a natural product sourced from Roemeria refracta, demonstrates antioxidative activity and impacts cardiovascular health [1] [2] [3]. |
| TN4164 |
Grandifloroside
|
|
TNF
|
|
Grandifloroside shows good antioxidative and potent anti-inflammatory activities, it also exhibits potent inhibitory activity against TNF-α and 5α-reductase, suggests that it might be developed as a source of potent anti... |
| TN3568 |
Calceolarioside A
|
|
Calcium Channel
,
Antifection
|
|
Calceolarioside A shows potent activity against visceral leishmaniasis. It can induce a dose-related aggregant effect on rabbit platelets, which may be partly related to a calcium-dependent mechanism. Calceolarioside A a... |
| T82478 |
Ellagic acid 4-O-α-L-arabinopyranoside
|
|
|
|
Ellagic acid 4-O-α-L-arabinopyranoside, extracted from Dimocarpus longan Lour. (syn. Euphoria longan Lam.), exhibits antioxidative activity [1]. |
| TN1919 |
(+)-Medioresinol
|
Medioresinol |
Beta Amyloid
,
ROS
,
Antifection
|
|
Medioresinol possesses antioxidative, a lesishmanicidal activity and cardiovascular disease risk reduction, it has antiamyloidogenic activity via reduction in the amount of α²-secretase, it is a potentially valuable anti... |
| TN1503 |
Cistanoside F
|
|
NADPH-oxidase
|
|
Cistanoside F shows vasorelaxant, and antioxidative effects, it shows a strong free radical scavenging activity on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and xanthine/xanthine oxidase (XOD) generated superoxide ani... |
| TN4094 |
Gallocatechin gallate
|
|
IL Receptor
,
NF-κB
,
ROS
,
MAPK
,
PPAR
,
Fatty Acid Synthase
|
|
Gallocatechin gallate has strong antioxidative, and anti-obesity activities, it inhibits 3T3-L1 differentiation and lipopolysaccharide induced inflammation through MAPK and NF-κB signaling; it also may have anti-diabeti... |
| TN4223 |
Homopterocarpin
|
|
Antifection
|
|
Homopterocarpin and Pterocarpus extract offer gastroprotection against indomethacin- induced ulcer by antioxidative mechanism and the modulation of gastric homeostasis, homopterocarpin may be responsible for, or contribu... |
| TN4840 |
Psoromic acid
|
|
Others
|
|
Psoromic acid is a selective and covalent rab-prenylation inhibitor targeting autoinhibited RabGGTase, it shows antibacterial activities against Streptococcus gordonii and Porphyromonas gingivalis, and it is an effective... |
| TN4471 |
Lysicamine
|
|
IL Receptor
,
Antifection
|
|
Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and a... |
